RG3

§ Overview

A ginsenoside compound derived from Panax ginseng that has gained attention in the peptide community for its metabolic and anti-cancer properties. While technically a triterpenoid saponin rather than a peptide, it's widely discussed alongside peptide protocols for its complementary fat-loss and anti-inflammatory effects.

§ Mechanism

Inhibits angiogenesis in tumors, modulates AMPK signaling for metabolic benefits, reduces NF-κB mediated inflammation, and enhances insulin sensitivity. Inhibits adipocyte differentiation and promotes brown adipose tissue activation for thermogenesis.

§ Common Uses

• → Fat loss
• → Anti-inflammatory
• → Metabolic support
• → Anti-cancer adjuvant
• → Insulin sensitivity

§ Reported Side Effects

• · GI upset (oral)
• · Insomnia
• · Headache

§ Research, Experiences & Trends