Index · 30 entries
The Catalogue.
Every peptide in the codex. Filter by category, sort by what matters to you. Each entry links through to a full research dossier.
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PC-005 · GLP-1
Tirzepatide
Mounjaro
A dual GIP/GLP-1 receptor agonist that has shown even greater efficacy than semaglutide for weight loss and glycemic control. Tirzepatide represents the next generation of incretin-based therapies, simultaneously targeting two key metabolic pathways.
896 exp · 189 papers · +52%
PC-004 · GLP-1
Semaglutide
Ozempic
A GLP-1 receptor agonist that has revolutionised the treatment of type 2 diabetes and obesity. Semaglutide mimics the incretin hormone GLP-1, reducing appetite, slowing gastric emptying, and improving insulin secretion. It has become one of the most prescribed weight-loss medications globally.
1247 exp · 312 papers · +45%
PC-029 · GLP-1
Retatrutide
LY3437943
A triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously — the first 'triple G' therapy. In Phase 2 trials, Retatrutide produced up to 24% body weight loss at 48 weeks, the highest ever recorded for an anti-obesity drug. Currently in Phase 3 trials by Eli Lilly.
23 exp · 14 papers · +38%
PC-024 · longevity
NAD+
Nicotinamide Adenine Dinucleotide
While technically a coenzyme rather than a peptide, NAD+ is included here due to its centrality in the longevity/biohacking community. NAD+ levels decline ~50% between ages 40-60. It's essential for cellular energy production, DNA repair, and sirtuin activation. Supplemented via precursors (NMN, NR) or direct IV/subcutaneous NAD+.
234 exp · 156 papers · +28%
PC-030 · GLP-1
Survodutide
BI 456906
A dual GLP-1 and glucagon receptor agonist developed by Boehringer Ingelheim. Survodutide represents a different approach to metabolic disease by combining GLP-1 effects with glucagon's ability to increase energy expenditure and reduce liver fat. Showing strong results in NASH/MASH clinical trials.
12 exp · 9 papers · +25%
PC-001 · regenerative
BPC-157
Body Protection Compound-157
A pentadecapeptide derived from human gastric juice. BPC-157 has shown remarkable regenerative properties in animal studies, promoting healing of tendons, ligaments, muscles, and the gastrointestinal tract. It's one of the most discussed peptides in the biohacking community for injury recovery.
342 exp · 87 papers · +23%
PC-022 · longevity
MOTS-c
Mitochondrial ORF of the 12S rRNA type-c
A mitochondrial-derived peptide (MDP) encoded by the mitochondrial genome. MOTS-c acts as a mitochondrial signal to the nucleus, regulating metabolic homeostasis and exercise biology. It's been called an 'exercise mimetic' for its ability to replicate some benefits of physical exercise.
76 exp · 35 papers · +21%
PC-013 · longevity
Epithalon
Epitalon
A synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. Epithalon is the most studied peptide in the context of telomerase activation and longevity. Research by Prof. Vladimir Khavinson showed it could extend lifespan in animal models by activating telomerase.
145 exp · 32 papers · +19%
PC-007 · growth-hormone
Ipamorelin
IPA
A selective growth hormone secretagogue that stimulates GH release without significantly affecting cortisol, prolactin, or other hormones. Considered the 'cleanest' GHRP due to its selectivity. Frequently combined with CJC-1295 for enhanced GH pulsatility.
289 exp · 19 papers · +18%
PC-023 · longevity
SS-31
Elamipretide
A mitochondria-targeted tetrapeptide that concentrates 1000-5000x in mitochondria. SS-31 stabilises cardiolipin, a critical phospholipid in the inner mitochondrial membrane, restoring electron transport chain function. Currently in clinical trials for heart failure and mitochondrial diseases.
54 exp · 67 papers · +17%
PC-019 · melanocortin
Melanotan II
MT-II
A synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that stimulates melanogenesis (skin tanning) without UV exposure. Melanotan II also has effects on sexual arousal, appetite suppression, and fat loss. PT-141 was derived from this peptide.
312 exp · 27 papers · +16%
PC-002 · regenerative
TB-500
Thymosin Beta-4
A synthetic version of Thymosin Beta-4, a naturally occurring peptide found in virtually all human and animal cells. TB-500 promotes cell migration, blood vessel growth, and wound healing. Widely used in veterinary medicine and popular among athletes for injury recovery.
198 exp · 62 papers · +15%
PC-012 · nootropic
Semax
ACTH 4-10 analogue
A synthetic analogue of ACTH (adrenocorticotropic hormone) fragment 4-10, developed in Russia and approved there as a nootropic drug. Semax enhances memory, attention, and cognitive function without hormonal side effects. It's been used clinically for stroke recovery and cognitive impairment.
156 exp · 45 papers · +14%
PC-020 · antimicrobial
KPV
Lys-Pro-Val
A naturally occurring tripeptide derived from the C-terminal end of alpha-MSH (alpha-melanocyte-stimulating hormone). KPV has potent anti-inflammatory properties and has shown promise in treating inflammatory bowel disease (IBD), skin conditions, and infections. It works without the tanning/sexual effects of full melanocortin peptides.
87 exp · 18 papers · +13%
PC-006 · growth-hormone
CJC-1295
CJC-1295 DAC
A synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce and release growth hormone. The DAC (Drug Affinity Complex) version binds to albumin, extending its half-life significantly. Often stacked with Ipamorelin for synergistic effects.
234 exp · 28 papers · +12%
PC-008 · regenerative
GHK-Cu
Copper Peptide
A naturally occurring copper complex of the tripeptide GHK (glycyl-L-histidyl-L-lysine). Found in human plasma, saliva, and urine. GHK-Cu declines with age and has been shown to promote wound healing, attract immune cells, stimulate collagen synthesis, and have anti-aging effects on skin.
178 exp · 56 papers · +11%
PC-026 · nootropic
Dihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
An oligopeptide derived from angiotensin IV that is reportedly 10 million times more potent than BDNF at promoting new neural connections. Dihexa was developed at Washington State University and has shown remarkable cognitive enhancement in animal studies, particularly for memory restoration.
45 exp · 8 papers · +11%
PC-017 · growth-hormone
Tesamorelin
Egrifta
A synthetic analogue of growth hormone-releasing hormone (GHRH) that is FDA-approved for reducing excess abdominal fat in HIV-infected patients with lipodystrophy. Tesamorelin is the only GHRH analogue with FDA approval, making it the most clinically validated GH-releasing peptide.
112 exp · 48 papers · +10%
PC-011 · nootropic
Selank
TP-7
A synthetic analogue of the immunomodulatory peptide tuftsin, developed at the Institute of Molecular Genetics in Russia. Selank has anxiolytic and nootropic properties, approved in Russia for treatment of anxiety and neurasthenia. It modulates mood without sedation or addiction potential.
123 exp · 38 papers · +9%
PC-003 · melanocortin
PT-141
Bremelanotide
A melanocortin receptor agonist FDA-approved for hypoactive sexual desire disorder (HSDD) in premenopausal women. Unlike PDE5 inhibitors (Viagra), PT-141 works through the central nervous system, affecting sexual desire rather than blood flow mechanics.
156 exp · 34 papers · +8%
PC-021 · antimicrobial
LL-37
Cathelicidin
The only human cathelicidin antimicrobial peptide. LL-37 is part of the innate immune system, produced by immune cells, epithelial cells, and keratinocytes. It has broad-spectrum antimicrobial activity against bacteria, viruses, and fungi, plus immunomodulatory and wound healing properties.
65 exp · 89 papers · +8%
PC-009 · immune
Thymosin Alpha-1
Ta1
A 28-amino acid peptide originally isolated from thymic tissue. Thymosin Alpha-1 is a potent immune modulator that enhances T-cell function and has been approved in over 30 countries for treatment of hepatitis B and C. It's used off-label for immune support and cancer adjuvant therapy.
89 exp · 124 papers · +7%
PC-027 · nootropic
PE-22-28
Spadin analogue
A heptapeptide derived from the Sortilin protein that acts as an antagonist of the TREK-1 potassium channel. PE-22-28 has shown rapid-onset antidepressant-like effects in animal studies, working within 4 days compared to weeks for SSRIs. It represents a novel mechanism for treating depression.
34 exp · 12 papers · +7%
PC-018 · metabolic
AOD-9604
Anti-Obesity Drug 9604
A modified fragment of human growth hormone (amino acids 176-191) specifically designed for fat loss without the growth-promoting effects of full GH. AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat storage). It was developed as an anti-obesity drug.
98 exp · 15 papers · +6%
PC-025 · nootropic
Cerebrolysin
FPF 1070
A multi-peptide mixture derived from porcine brain tissue, containing neurotrophic factors and free amino acids. Cerebrolysin has been approved in many countries (not US/UK) for stroke, traumatic brain injury, and dementia. It's one of the most clinically studied neuropeptide preparations.
89 exp · 134 papers · +6%
PC-010 · nootropic
DSIP
Delta Sleep-Inducing Peptide
A neuropeptide originally isolated from rabbit brain cerebral venous blood during induced sleep. DSIP modulates sleep architecture, stress responses, and pain perception. Despite its name, it doesn't directly induce sleep but rather normalises sleep patterns and improves sleep quality.
67 exp · 42 papers · +5%
PC-015 · growth-hormone
GHRP-2
Growth Hormone Releasing Peptide 2
A synthetic hexapeptide growth hormone secretagogue. GHRP-2 is considered the strongest GH releaser in the GHRP family, producing the highest GH pulse. It's more potent than GHRP-6 but with similar side effects including appetite stimulation and cortisol/prolactin increases.
143 exp · 31 papers · +4%
PC-028 · metabolic
RG3
Ginsenoside Rg3
A ginsenoside compound derived from Panax ginseng that has gained attention in the peptide community for its metabolic and anti-cancer properties. While technically a triterpenoid saponin rather than a peptide, it's widely discussed alongside peptide protocols for its complementary fat-loss and anti-inflammatory effects.
56 exp · 67 papers · +4%
PC-014 · growth-hormone
GHRP-6
Growth Hormone Releasing Peptide 6
One of the original growth hormone secretagogues. GHRP-6 stimulates the pituitary to release growth hormone through the ghrelin receptor. It's potent but less selective than newer alternatives like Ipamorelin, notably causing significant hunger spikes due to ghrelin pathway activation.
167 exp · 24 papers · +3%
PC-016 · growth-hormone
Hexarelin
Examorelin
A synthetic hexapeptide GH secretagogue with the strongest initial GH release of any GHRP. However, Hexarelin is notable for significant desensitisation — the GH response diminishes with continuous use. It also has unique cardioprotective properties independent of GH release.
78 exp · 22 papers · +2%