PEPTIDE_CODEX

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PC-013 · longevity · epithalon

Epithalon

Epitalon

Also: Epithalone · AEDG peptide

Ala-Glu-Asp-Gly

human trialanimal studyin vitro

A synthetic tetrapeptide based on the natural peptide epithalamin, produced by the pineal gland. Epithalon is the most studied peptide in the context of telomerase activation and longevity. Research by Prof. Vladimir Khavinson showed it could extend lifespan in animal models by activating telomerase.

Activates telomerase (hTERT), the enzyme that lengthens telomeres — the protective caps on chromosomes that shorten with each cell division. Also stimulates melatonin production from the pineal gland and normalises circadian rhythms.

  • Anti-aging/longevity
  • Telomere lengthening
  • Sleep improvement
  • Circadian regulation
  • Immune support
  • · Injection site irritation
  • · Drowsiness

Mechanism of Action

Activates telomerase (hTERT), the enzyme that lengthens telomeres — the protective caps on chromosomes that shorten with each cell division. Also stimulates melatonin production from the pineal gland and normalises circadian rhythms.

Common Uses

Anti-aging/longevityTelomere lengtheningSleep improvementCircadian regulationImmune support

Dosage & Pharmacology

DOSAGE RANGE: 5-10 mg daily for 10-20 days (subcutaneous), cycled
HALF-LIFE: ~2-3 hours
MOL. WEIGHT: 390.35 Da
SEQUENCE:
Ala-Glu-Asp-Gly
Dosage information is for research reference only. Not a recommendation.

Known Side Effects

  • Injection site irritation
  • Drowsiness

Legal Status

US:Not FDA-approved, research chemical
UK:Not approved
EU:Not approved
RU:Clinical use under research

Related Peptides

View all Epithalon research on PubMed