PC-016 · growth-hormone · hexarelin
Hexarelin
Examorelin
Also: HEX
§ Overview
A synthetic hexapeptide GH secretagogue with the strongest initial GH release of any GHRP. However, Hexarelin is notable for significant desensitisation — the GH response diminishes with continuous use. It also has unique cardioprotective properties independent of GH release.
§ Mechanism
Strong ghrelin receptor (GHSR) agonist producing powerful GH pulses. Additionally activates cardiac receptors (CD36) providing cardioprotective effects independent of GH. Receptor desensitisation occurs after 4-8 weeks of continuous use.
§ Common Uses
- → GH release (short-term)
- → Cardioprotection
- → Fat loss
- → Muscle growth
§ Reported Side Effects
- · Cortisol/prolactin elevation
- · Water retention
- · Receptor desensitisation
- · Hunger
§ Research, Experiences & Trends
Mechanism of Action
Strong ghrelin receptor (GHSR) agonist producing powerful GH pulses. Additionally activates cardiac receptors (CD36) providing cardioprotective effects independent of GH. Receptor desensitisation occurs after 4-8 weeks of continuous use.
Common Uses
Dosage & Pharmacology
Known Side Effects
- • Cortisol/prolactin elevation
- • Water retention
- • Receptor desensitisation
- • Hunger